abstract：RATIONALE AND OBJECTIVES:To assess whether differences in cerebral atrophy and white matter lesions or in the presence of lactate and lipid signals can explain the observed differences in brain choline, creatine, and N-acetylaspartate levels between healthy elderly women and men. METHODS:In addition to standard magnet...

journal_title：Investigative radiology

authors： Sijens PE,Den Heijer T,De Leeuw FE,De Groot JC,Achten E,Heijboer RJ,Hofman A,Breteler MM,Oudkerk M

更新日期：2001-10-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:The purpose of this study was to evaluate the effects of variation in design parameters on the resultant radial force. We evaluated the influence of wire gauge, leg length, and number of bends on the radial force produced by z stents and compared these with radial forces produced by commercial s...

journal_title：Investigative radiology

authors： Snowhill PB,Nosher JL,Siegel RL,Silver FH

更新日期：2001-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To determine whether vascular endothelial growth factor (VEGF) is a histopathological factor influencing contrast enhancement of hepatocellular carcinoma (HCC) on computed tomography (CT). METHODS:Twenty-two nodular HCCs underwent multiphase helical CT and surgery. Tumor size, histological gra...

journal_title：Investigative radiology

authors： Kwak BK,Shim HJ,Park ES,Kim SA,Choi D,Lim HK,Park CK,Chung JW,Park JH

更新日期：2001-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Diabetic patients frequently suffer contrast media-induced nephropathy. Hyperglycemia in diabetes mellitus causes gradual deterioration of glomerular mesangial cells (MCs) in the kidney. In this study, the authors investigated the response of rat MCs cultured in high-glucose medium to diatrizoa...

journal_title：Investigative radiology

authors： Wasaki M,Sugimoto J,Shirota K

更新日期：2001-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To present the results of two studies conducted to evaluate the pharmacokinetics and safety of iomeprol in healthy volunteers and in patients with various degrees of renal impairment. METHODS:In these two open-label, single-dose, phase I studies, a 50-mL dose of iomeprol 400 was administered i...

journal_title：Investigative radiology

authors： Lorusso V,Taroni P,Alvino S,Spinazzi A

更新日期：2001-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare the visibility and localization of extratemporal cortical lesions in extratemporal epilepsy by using curved reconstruction (CR) and three-dimensional surface rendering (3D SR) of 3D-acquired MR images and to study the degree of confidence with which localizations are made, particular...

journal_title：Investigative radiology

authors： Meiners LC,Scheffers JM,De Kort GA,Burger H,Van Huffelen AC,Van Rijen PC,Van Veelen CW

更新日期：2001-04-01 00:00:00

abstract：UNLABELLED:Szapiro D, Ghaye B, Willems V, et al. Evaluation of CT time-density curves of lower-limb veins. Invest Radiol 2001;36:164-169. RATIONALE AND OBJECTIVES:To evaluate time-density curves of the lower-limb veins for optimization of CT venography. METHODS:Fifty patients referred for chest CT were randomized int...

journal_title：Investigative radiology

authors： Szapiro D,Ghaye B,Willems V,Zhang L,Albert A,Dondelinger RF

更新日期：2001-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The suitability of paramagnetic complexes as magnetic resonance contrast agents depends on various factors such as their relaxivity, stability, selectivity, and the inertness toward transmetallation by endogenous ions. The transmetallation of a series of 18 gadolinium complexes by the Zn2+ ion ...

journal_title：Investigative radiology

authors： Laurent S,Elst LV,Copoix F,Muller RN

更新日期：2001-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To summarize the chemical synthesis, physicochemical characterization, pharmacokinetic behavior, and biological evaluation of P743, a new macromolecular iodinated contrast medium. METHODS:The synthesis and molecular modeling of the iodinated macromolecule P743 are described. The pharmacokineti...

journal_title：Investigative radiology

authors： Idée JM,Port M,Robert P,Raynal I,Prigent P,Dencausse A,Le Greneur S,Tichkowsky I,Le Lem G,Bourrinet P,Mugel T,Benderbous S,Devoldere L,Bourbouze R,Meyer D,Bonnemain B,Corot C

更新日期：2001-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Echogenic antibody-conjugated anionic liposomes have been developed that allow directed tissue targeting and acoustic enhancement. These are not efficient for gene delivery. A cationic formulation that allows directed gene delivery while retaining acoustic properties may provide more efficient ...

journal_title：Investigative radiology

authors： Tiukinhoy SD,Mahowald ME,Shively VP,Nagaraj A,Kane BJ,Klegerman ME,MacDonald RC,McPherson DD,Matsumura JS

更新日期：2000-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess the abilities of dynamic diffusion-weighted MRI to demonstrate the effects in vivo of a high-viscosity iodinated contrast agent on medullary and cortical blood flow in the rat kidney. METHODS:Dynamic diffusion-weighted, echoplanar MR images obtained from five b-value single-shot acqu...

journal_title：Investigative radiology

authors： Laissy JP,Menegazzo D,Dumont E,Piekarski JD,Karila-Cohen P,Chillon S,Schouman-Claeys E

更新日期：2000-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Very small dextran-coated magnetite particles were developed. These particles can be used either as immunospecific contrast agents for MRI by coupling to antibodies or as an interstitial contrast agent. METHODS:The particles were synthesized from iron chloride/dextran solutions. Size was evalu...

journal_title：Investigative radiology

authors： Grimm J,Karger N,Lüsse S,Winoto-Morbach S,Krisch B,Müller-Hülsbeck S,Heller M

更新日期：2000-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Density of trabecular bone structures in human heel bones was assessed by 3D magnetic resonance (MR) gradient echo imaging (GEI) with multiple echoes. Different spatial resolutions were applied to investigate the influence of the pixel size on signal characteristics in GEI and to find suitable ...

journal_title：Investigative radiology

authors： Machann J,Schnatterbeck P,Raible A,Lutz O,Claussen CD,Schick F

更新日期：2000-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the attenuation, size, and volume of the pericardial sinuses and recesses by using electrocardiographically triggered, noncontrast-enhanced electron beam tomography (EBT) and to consider its relation with sex, age, and heart volume. METHODS:Findings in 213 consecutive patients with...

journal_title：Investigative radiology

authors： Budoff MJ,Lu B,Mao S,Bakhsheshi H,Zhuang N,Liu SC,French WJ

更新日期：2000-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To establish a pig model suitable for imitating pulmonary emboli to facilitate research in the diagnosis of pulmonary embolism. METHODS:Thirteen animals were anesthetized, mechanically ventilated, and subjected to pulmonary artery catheterization initiated from the right external jugular vein....

journal_title：Investigative radiology

authors： Amundsen T,Kvaerness J,Aadahl P,Waage A,Bjermer L,Odegård A,Haraldseth O

更新日期：2000-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a new automated calibration method for vessel measurements in vascular x-ray images. METHODS:Radiopaque marker bands mounted equidistantly on a small catheter were acquired in vitro at five image intensifier (II) sizes in x-ray projection images. The positions of the marker centers ...

journal_title：Investigative radiology

authors： Van Assen HC,Vrooman HA,Egmont-Petersen M,Bosch HG,Koning G,Van Der Linden EL,Goedhart B,Reiber JH

更新日期：2000-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To characterize the long-term effects of therapeutic doses of ionizing radiation on the uptake and distribution of percutaneously delivered particulate contrast media in normal lymph nodes. METHODS:Two milliliters of an iodinated nanoparticle suspension (76 mg I/mL) was injected subcutaneously...

journal_title：Investigative radiology

authors： Wisner ER,Théon A,Griffey SM,McIntire GL

更新日期：2000-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the use of a new thrombus-specific ultrasound contrast agent, MRX-408, in the ultrasonic detection of thrombus in arteriovenous (AV) fistulae. METHODS:Six purpose-bred mongrels with two AV fistulae each were imaged with gray-scale ultrasound 7 weeks after graft implantation before ...

journal_title：Investigative radiology

authors： Unger E,Metzger P 3rd,Krupinski E,Baker M,Hulett R,Gabaeff D,Mills J,Ihnat D,McCreery T

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:As an imaging modality for follow-up during continuous or repeated hepatic arterial infusion chemotherapy using a hepatic intra-arterial indwelling catheter, the usefulness of CT while infusing contrast through the indwelling catheter (reservoir port) was examined. METHODS:Using reservoir ports implanted in ...

journal_title：Investigative radiology

authors： Morimoto M,Satake M,Sekiguchi R,Haruno M,Moriyama N

更新日期：1999-12-01 00:00:00

abstract：:Recent experimental data underlies the role of hypoxic tubular injury in the pathophysiology of radiocontrast nephropathy. Although systemic transient hypoxemia, increased blood viscosity, and a leftward shift of the oxygen-hemoglobin dissociation curve may all contribute to intrarenal hypoxia, imbalance between oxyge...

journal_title：Investigative radiology

authors： Heyman SN,Reichman J,Brezis M

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the degree of ischemic changes of the small intestine after arterial embolization of proximal or distal arteries with Gelfoam particles and coils in dogs. METHODS:Superselective arterial embolization in 18 dogs was performed using a coaxial catheter system. Gelfoam occlusion of the proximal level...

journal_title：Investigative radiology

authors： Han YM,Lee JM,Jin KY,Lee SY,Kim CS

更新日期：1999-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the effect of the transverse ligament on translation of the menisci. METHODS:Six cadaveric knees were examined by MR imaging inside a positioning device before and after transecting the transverse ligament. The knees were examined at various positions: extension, 30 degrees of flex...

journal_title：Investigative radiology

authors： Muhle C,Thompson WO,Sciulli R,Pedowitz R,Ahn JM,Yeh L,Clopton P,Haghighi P,Trudell DJ,Resnick D

更新日期：1999-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Ureteric jet index (UJI), a newly developed technique derived from color Doppler ultrasonography, may hold promise in evaluating renal function because of its ability to evaluate individual renal function and the use of nonionizing radiation. To assess the usefulness of UJI, the authors in this...

journal_title：Investigative radiology

authors： Chiu NT,Wu CC,Yao WJ,Tu DG,Lee BF,Tong YC,Pan CC

更新日期：1999-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the feasibility of mechanical thrombectomy in occluded hemodialysis access shunts by using a newly developed 5F pigtail rotation catheter. METHODS:Thrombosed hemodialysis access shunts were simulated by clotted bovine blood in silicone tubing (diameter 6 mm). After retrograde and a...

journal_title：Investigative radiology

authors： Wildberger J,Schmitz-Rode T,Wein BB,Günther RW

更新日期：1999-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:High signal intensity in the basal ganglia on T1-weighted MR imaging has been reported in chronic manganese (Mn) poisoning. However, the exact meaning of the high signal intensity remains unclear: does it result from Mn itself, secondary pathologic changes of the brain tissue, or both? The goal...

journal_title：Investigative radiology

authors： Kim SH,Chang KH,Chi JG,Cheong HK,Kim JY,Kim YM,Han MH

更新日期：1999-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the short-term effects of a new nitinol stent on canine arteries. METHODS:Eighteen nitinol mesh stents were placed in abdominal aortas, common iliac arteries, and renal arteries of six dogs. Angiography was performed to evaluate the patency rates and structural changes of arteries ...

journal_title：Investigative radiology

authors： Lee KW,Park JH,Chung JW,Kim WS,Lee W,Yeon KM

更新日期：1999-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To investigate image mottle in conventional CT images of the abdomen as a function of radiographic technique factors and patient size. METHODS:Water-filled phantoms simulating the abdomens of adult (32 cm in diameter) and pediatric (16 cm in diameter) patients were used to investigate image mo...

journal_title：Investigative radiology

authors： Ende JF,Huda W,Ros PR,Litwiller AL

更新日期：1999-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To demonstrate the usefulness of a model of the parenchymous vascularization to evaluate texture analysis methods. METHODS:Slices with thickness varying from 1 to 4 mm were reformatted from a 3D vascular model corresponding to either normal tissue perfusion or local hypervascularization. Param...

journal_title：Investigative radiology

authors： Rolland Y,Bézy-Wendling J,Duvauferrier R,Coatrieux JL

更新日期：1999-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Magnetic resonance imaging (MRI) techniques seem to be very promising for 3D dosimetry studies, but long imaging acquisition time limits their use. A new fast T1 mapping protocol, easy to implement on a conventional MR imager, has been used to determine dose distributions on Fricke gels. METHO...

journal_title：Investigative radiology

authors： Calmet C,Vincensini D,Bonnet J,Bertino C,Catala A,Martinez M,Joffre F

更新日期：1999-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:This study sought to evaluate prospectively the diagnostic potential of unenhanced and enhanced color Doppler and power Doppler for the differentiation of tumors and tumorlike lesions of the breast. METHODS:Ninety-two patients with 110 tumors or tumorlike lesions of the breast were investigate...

journal_title：Investigative radiology

authors： Schroeder RJ,Maeurer J,Vogl TJ,Hidajat N,Hadijuana J,Venz S,Weber S,Felix R

更新日期：1999-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate different vein graft-coated stent systems in the endovascular treatment of experimental arteriovenous fistulae (AVF) in a canine model. METHODS:Bilateral carotid-to-external jugular vein AVF were created. Two balloon-expandable tantalum stents (Strecker stent), two self-expanding n...

journal_title：Investigative radiology

authors： Schellhammer F,Wahkloo AK,Nagursky H,Schumacher M

更新日期：1999-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Ultrasound can cause destruction of microbubble contrast agents used to enhance medical ultrasound imaging. This study sought to characterize the dynamics of this interaction by direct visual observation of microbubbles during insonification in vitro by a medical ultrasound imaging system. MET...

journal_title：Investigative radiology

authors： Klibanov AL,Ferrara KW,Hughes MS,Wible JH Jr,Wojdyla JK,Dayton PA,Morgan KE,Brandenburger GH

更新日期：1998-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors determine the value of contrast-enhanced, three-dimensional (3D) magnetic resonance angiography (MRA) in the assessment of the renal arteries in comparison with conventional arteriography (CA). METHODS:One hundred three patients (71 m, 32 f) were evaluated with both CA and 3D MRA. ...

journal_title：Investigative radiology

authors： Hany TF,Leung DA,Pfammatter T,Debatin JF

更新日期：1998-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors compare the magnetic resonance (MR) phase contrast flow velocity measurements in varying concentric stenoses with invasive measurements obtained with a Doppler guidewire. METHODS:Flow velocity measurements were obtained using a calibrated 0.018 inch 12 MHz Doppler guidewire and a 1...

journal_title：Investigative radiology

authors： Hoppe M,Heverhagen JT,Froelich JJ,Kunisch-Hoppe M,Klose KJ,Wagner HJ

更新日期：1998-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors used gadolinium (Gd) chelate as a T1, T2, and T2* enhancing agent in reperfused myocardial infarction to compare the appearance of reperfused myocardial infarction on spin echo and gradient echo magnetic resonance (MR) sequences. METHODS:Rats (n = 28) were subjected to reperfused m...

journal_title：Investigative radiology

authors： Geschwind JF,Saeed M,Wendland MF,Higgins CB

更新日期：1998-07-01 00:00:00

abstract：:The effect of three iodinated contrast media (CM) on human plasma butyrylcholinesterase (BuChE) activity was studied during the intravenous pyelography (i.v.P). BuChE is an enzyme that participates in the metabolism of acetylcholine and hydrolyzes food esters and drugs such as nondepolarizing muscle relaxants and loca...

journal_title：Investigative radiology

authors： Mironidou M,Ximitidou O,Christopoulos S,Kokkas B

更新日期：1998-05-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:Magnetic resonance (MR) scan technique and lesion detectability were evaluated using a newly developed spinal abscess model in the New Zealand White rabbit. METHODS:To create the lesion, an epidural needle was inserted under fluoroscopic guidance in the lumbar region and advanced to penetrate t...

journal_title：Investigative radiology

authors： Runge VM,Williams NM,Lee C,Timoney JF

更新日期：1998-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Air microemboli may damage the cerebral microvasculature. The aim of this study was to evaluate the safety of ultrasound contrast agents composed of air microspheres with regard to cerebral damage when administered into the arterial system (ie, when not filtered by the capillary system of the l...

journal_title：Investigative radiology

authors： Haggag KJ,Russell D,Walday P,Skiphamn A,Torvik A

更新日期：1998-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:This study was conducted to determine whether significant reduction in radiation dose (250 mAs-->50 mAs), in chest computed tomography (CT) using volume acquisition affects image quality or the detectability of pathologic findings in the lung and mediastinum. METHODS:Phantom studies were condu...

journal_title：Investigative radiology

authors： Takahashi M,Maguire WM,Ashtari M,Khan A,Papp Z,Alberico R,Campbell W,Eacobacci T,Herman PG

更新日期：1998-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The object of this study was to determine by flow cytometry the cellular and DNA content of the washings of core biopsy samples and needles obtained during stereotactic core biopsies of clinically occult suspicious lesions. METHODS:Fourteen-gauge core multipass biopsy inner-needle saline washi...

journal_title：Investigative radiology

authors： Stomper PC,Budnick RM,Stewart CC

更新日期：1998-01-01 00:00:00